My colleague Cora Ng has been doing some research on the hurdles managers who work in anti-corruption face.
Over 100 of them responded to our survey and when asked for their top ten challenges said they were these:
1) Getting employee buy-in and commitment to true ethical behaviour
2) Getting support from top management and changing the view of compliance function as a mere cost centre
3) Fighting against the existing ‘turn-a-blind-eye’ culture, and the way ‘business has always been done’
4) Managing an effective global program that complies with different and sometimes contradicting local laws
5) Keeping abreast of ever increasing legislation and ensuring that new requirements are always met
For the next five in the list, have a look here.
I'm Tobias Webb, founder of Innovation Forum and Sustainable Wine. I write on this blog, with others, about areas of interest to me in supply chains, circular economy and sustainability in general. I hope you find it useful. I've worked in sustainability for about 20 years, and work with large companies, NGOs and governments all over the world. I often act as facilitator, at our conferences, and other meetings, either private or multi-stakeholder. I also work as a 'critical friend' advisor to companies on strategy and stakeholder engagement. I have a separate wine website on sustainability in wine at 
ethics and compliance solutions program
The link to the other 5 is not working (page not found). I think those five you listed is manageable as long as everybody in the company knows what actions are acceptable and not, ethically. This calls for an ethics and compliance training for everybody.